Working with solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our analysis interests include things like:
But how can morality, the dignity with the human being, my encounter of the this means of daily life, stick to from the motion of atoms? A purely naturalistic viewpoint fails here; a Christian standpoint, I feel, is a much more reasonable technique to interpret these facets of reality.’
, Groningen researchers present the outcome in their initiatives for making labs extra sustainable and supply tips for other labs.
Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style in 2005. (nl)
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Quite a few similar developments adopted, where by our team founded distinctive transistor variants such as single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled numerous transistors into little proof-of-principle Digital ceesdekker circuits.
Researching DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
The rotors harness Electricity from a nanoscale h2o and ion circulation which is created by a static chemical or electrochemical probable gradient inside the nanopore, which can be established via a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting methods to developing Vitality-transducing motors at nanoscale interfaces.
Bulk-surface coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
Tests pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
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2008, initial observation of protein-coated DNA translocation via nanopores; resolved the origin from the electrophoretic force on DNA in nanopores; discovered a significant velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization with the mechanical Homes of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.